Description
SEMAX
| CAS Number | 80714-61-0 |
| Alias | MEHFPGP ACTH(4–10) analog |
| IUPAC Name | L-methionyl-L-glutamyl-L-histidyl-L-phenylalanyl-L-prolyl-glycyl-L-proline |
| Molecular Formula | C37H51N9O10 |
| Molecular Weight | 751.86 g/mol |
Semax (MEHFPGP)
Semax is a synthetic heptapeptide (Met–Glu–His–Phe–Pro–Gly–Pro), structurally derived from the ACTH(4–10) fragment. It is commonly used in in vitro and in vivo preclinical research to investigate mechanisms related to neuronal regulation, peptide signaling, and central nervous system function. Due to its structure and interaction with neurochemical pathways, Semax remains a widely studied compound in cognitive and neurobiological research models.
Experimental Mechanisms (Laboratory Models Only)
Neurotrophic Pathway Investigation
Semax has been observed to modulate expression of neurotrophic factors such as brain-derived neurotrophic factor (BDNF) in cultured neuronal systems. These studies aim to explore peptide-related regulation of neuronal growth, survival, and synaptic development.
Neurochemical Signaling Models
In various experimental setups, Semax is used to study its effect on central monoamine levels, including dopamine and serotonin, particularly in neural circuits associated with motivation and attention.
Oxidative Stress & Inflammatory Marker Research
Research models have used Semax to explore responses to oxidative stress, inflammatory stimuli, and neuronal resilience under challenging conditions, including hypoxia or ischemia simulations.
Fast USA Domestic Shipping and Laboratory Standards
Sourced and shipped directly from USA suppliers, this Semax product ensures rapid delivery times and reliable customer service support. The domestic shipping advantage means faster processing, reduced customs delays, and better package tracking throughout delivery. All products meet laboratory-grade standards with proper documentation and quality certificates. The USA-based supply chain provides peace of mind regarding product authenticity, storage conditions, and regulatory compliance for research purposes.





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